What will happen if the secretion of parietal cells of gastric glands is blocked with an inhibitor?
What will happen if the secretion of parietal cells of gastric glands is blocked with an inhibitor?
The correct option is A In the absence of HCl secretion, inactive pepsinogen is not converted into the active enzyme pepsin.
The correct option is A.
Explanation of the correct option:
- Gastric secretions are produced by parietal cells, chief cells, D-cells, mucous cells, and other cells in the stomach.
- The stomach secretes water, electrolytes, hydrochloric acid, and glycoproteins.
- Protein digestion requires the presence of gastric acid.
- It also helps to reduce bacterial overgrowth and gastrointestinal illnesses.
- The small tubular glands generated by the stomach epithelial cells are known as gastric glands.
- The parietal cells are abundant on the sidewalls of the gastric glands.
- The parietal cells release hydrochloric acid as well as intrinsic substances that aid in the stomach's pH stability (about 1.5-2.0).
- Hydrochloric acid is used to convert pepsinogen to pepsin and prorenin to renin.
- In the absence of hydrochloric acid, inactive pepsinogen cannot be converted into active enzyme pepsin.
Explanation of the incorrect options:
Option B:
If the secretion of parietal cells of gastric glands is blocked with an inhibitor then gastric juice will not be deficient in chymosin.
Option C:
If the secretion of parietal cells of gastric glands is blocked with an inhibitor then enterokinase will not be affected and will be released from the duodenal mucosa, so trypsinogen is converted to trypsin.
Option D:
If the secretion of parietal cells of gastric glands is blocked with an inhibitor then gastric juice will not be deficient in pepsinogen.
Final answer: If the secretion of parietal cells of gastric glands is blocked with an inhibitor then in the absence of HCl secretion, inactive pepsinogen is not converted into the active enzyme pepsin.
In the absence of HCl secretion, inactive pepsinogen is not converted into the active enzyme pepsin.
The correct option is A.
Explanation of the correct option:
- Gastric secretions are produced by parietal cells, chief cells, D-cells, mucous cells, and other cells in the stomach.
- The stomach secretes water, electrolytes, hydrochloric acid, and glycoproteins.
- Protein digestion requires the presence of gastric acid.
- It also helps to reduce bacterial overgrowth and gastrointestinal illnesses.
- The small tubular glands generated by the stomach epithelial cells are known as gastric glands.
- The parietal cells are abundant on the sidewalls of the gastric glands.
- The parietal cells release hydrochloric acid as well as intrinsic substances that aid in the stomach's pH stability (about 1.5-2.0).
- Hydrochloric acid is used to convert pepsinogen to pepsin and prorenin to renin.
- In the absence of hydrochloric acid, inactive pepsinogen cannot be converted into active enzyme pepsin.
Explanation of the incorrect options:
Option B:
If the secretion of parietal cells of gastric glands is blocked with an inhibitor then gastric juice will not be deficient in chymosin.
Option C:
If the secretion of parietal cells of gastric glands is blocked with an inhibitor then enterokinase will not be affected and will be released from the duodenal mucosa, so trypsinogen is converted to trypsin.
Option D:
If the secretion of parietal cells of gastric glands is blocked with an inhibitor then gastric juice will not be deficient in pepsinogen.
Final answer: If the secretion of parietal cells of gastric glands is blocked with an inhibitor then in the absence of HCl secretion, inactive pepsinogen is not converted into the active enzyme pepsin.
