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Question

Which hormones can uncouple oxidative phosphorylation in high concentration?


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Solution

Hormones uncouple oxidative phosphorylation in high concentration:

  1. The uncoupling protein is a hormone called thermogenin that is present in mitochondria.
  2. It is responsible for the oxidative phosphorylation-produced decrease in the proton gradient.
  3. The process of thermogenin is the return of protons to the mitochondria.
  4. It is in charge of enhancing the inner mitochondrial membrane's permeability.
  5. The reactions of phosphorylation and electron transport are coupled.

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