Question

Which of the following events does not occur in the rough endoplasmic reticulum?

• A. protein glycosylation
• B. phospholipid synthesis
• C. cleavage of signal peptide
• D. protein folding

Answer 1

The correct option is B

phospholipid synthesis

The correct option is B

Explanation of the correct option:

1. Phospholipid synthesis occurs on the cytoplasmic face of the endoplasmic reticulum.
2. The smooth endoplasmic reticulum functions in many metabolic processes such as lipid synthesis.

Explanation of the incorrect options:

Option A

1. Protein glycosylation is an addition of carbohydrate moiety to a protein molecule.
2. The process takes place in the rough endoplasmic reticulum and Golgi bodies.

Option C

1. Signal peptides are found in proteins that are targeted to the endoplasmic reticulum.
2. They are cleaved in the rough endoplasmic reticulum.

Option D

1. Protein folding is the process of folding the protein into a 3-dimensional structure.
2. It takes place in the compartment of the rough endoplasmic reticulum.

Final answer: Phospholipid synthesis is the event that does not takes place in the rough endoplasmic reticulum.