The chromosome was first discovered by Walther Flemming.
He named the thread-like structure that is present in the nucleus as chromatin in 1878.
Karl Nageli observed the rod shape of chromosomes in the plant cell in 1842 and called them transitory cytoblasts, which were later identified as chromosomes.
DNA molecules are highly organised and packaged in eukaryotic cells to fit inside the nucleus.
DNA wrapped around histone octamer makes the repeating unit of chromatin called a nucleosome.
Nucleosomes appear as beads on a string of chromatin thread.
Chromatin fibres further condense and appear as chromosomes at the metaphase stage of the cell division.