Question

Why is immortalization difficult in human cells?

Answer 1

Immortalization:

1. When developed for extensive stretches in culture, cells in a populace can gather unconstrained transformations that forestall senescence, bringing about deified or laid out cell lines that fill endlessly in culture.
2. The idea of the transformations that cause deification fluctuates from cell line to cell line.
3. In numerous rat cells, deification is a generally fast occasion that is accomplished by changes in parts that capture the cell cycle in light of non-physiological culture conditions.
4. In human cells, deification is more troublesome in light of the fact that it requires numerous transformations that both inactivate these parts and increment the movement of telomerase, permitting the development of stable telomeres.