Central Dogma of Molecular Biology

Q. Transcription takes place in the _________ and translation occurs in the _______.

1. cytoplasm, nucleus
2. ribosome, nucleus
3. nucleus, mitochondria
4. nucleus, cytoplasm

Q.

In the Griffith experiment, which of the following resulted in the death of the mice?

1. Live R strain bacteria $\to$ Inject into mice

2. Heat-killed S strain bacteria $\to$ Inject into mice

3. Live S strain bacteria $\to$ Inject into mice

4. Heat-killed R strain bacteria $\to$ Inject into mice

Q. Bacterial DNA protects its own DNA from being cut up by the restriction enzymes present in the cell because _____________ .

1. bacterial DNA has no recongition sequences
2. some of the nucleotides have caps of methyl group
3. recognition sequences are covered with proteins
4. only foriegn DNA can activate the restriction enzymes

Q.

How does RNA occur as genetic material in some plant viruses?

Q.

What Is Post-transcriptional regulation of gene expression?

Q.

What is the difference between repressor and corepressor?

Q. What is called Central Dogma in molecular biology?

Q.

Organism produced from two parents is an example of:

1. Evolution

2. Sexual reproduction

3. Binary fission

4. Asexual reproduction

Q. What is a codon?

1. A group of three nucleotide sequences.
2. The nucleotide units between the start and stop codes.
3. The nucleotide sequence that serves as the instructions for a protein.
4. A single nucleotide in an mRNA sequence.
5. The sequence of nucleotide that signals the start or shop of protein synthesis.

Q. According to the lac operon concept, which functional unit of the bacterial genetic material is responsible for suppressing the activity of the operator gene in the absence of lactose?

1. Structural gene
2. Promoter gene
3. Regulator gene
4. Repressor protein

Q. Central dogma in molecular biology is

1. RNA ---> DNA ---> Protein
2. DNA -----> RNA ---> Protein
3. RNA ---> Protein ----> DNA
4. DNA ---> Protein ---> RNA

Q. What is central dogma?

Q. Central dogma of molecular biology is

1. DNA $\rightleftharpoons$ RNA $\to$ Proteins
2. RNA $\to$ Proteins $\to$ DNA
3. RNA $\to$ DNA $\to$Proteins
4. DNA $\to$ RNA $\to$ Proteins

Q.

Regarding the assertion and reason; choose the correct option.

Assertion [A]: Cyclin and CDK complex constitute various checkpoints to ensure correct sequence and product in each phase of cell division .

Reason [R]: The Cyclin and CDK complex acts as molecular regulators or switches.

1. Assertion [A] is True and Reason [R] is False.

2. Reason [R] is True and Assertion [A] is False.

3. Assertion [A] is True and Reason [R] is True but is an incorrect explanation to [A].

4. Assertion [A] is True and Reason [R] is True and is a correct explanation to [A].

Q. Where does the process of transcription takes place?

1. Nucleus
2. Ribosome
3. Cytoplasm
4. Endoplasmic Reticulum

Q. 'Central Dogma' was proposed by whom?

1. Crick
2. Beadle and Tatum
3. Temin and Baltimore
4. Klug

Q.

Do humans have antibiotic resistance genes?

Q. Each cycle of PCR essentially double the amount of DNA from previous cycle. Explain. Also, give the applications of PCR in any two areas.

Q. In the operon model, RNA polymerase binds to

1. Structural gene
2. Promoter
3. Regulator
4. Operator

Q. Choose the correct answer from the alternatives given :
The given flow chart represents the flow of genetic information between biomolecules. identify the processes A, B, C and D and select the correct option.

1. A - Replication, B - Reverse Transcription, C - Transcription, D - Translation
2. A - Replication, B - Transcription, C - Reverse Transcription, D - Translation
3. A - Replication, B - Transcription, C - Translation, D - Reverse Transcription
4. A - Translation, B - Transcription, C- Replication, D - Reverse Transcription

Q. Which is the most important factor for continuation of a species from evolutionary point of view?

1. Formation of gametes

2. Replication of genetic material

3. Synthesis of proteins

4. \N

Q. Information flow or central dogma of molecular biology is

1. RNA $\to$ Proteins $\to$ DNA
2. proteins $\to$ RNA $\to$ DNA
3. RNA $\to$ DNA $\to$ Proteins
4. DNA $\to$ RNA $\to$ Proteins

Q. The given flow chart shows central dogma reverse.
Enzymes used in processes A, B and C are respectively

1. A - DNA dependent DNA polymerase, B - RNA dependent DNA polymerase, C - DNA dependent RNA polymerase
2. A - DNA dependent DNA polymerase, B - DNA dependent RNA polymerase, C - RNA dependent DNA polymerase
3. A - DNA dependent RNA polymerase, B - DNA dependent DNA polymerase, C - RNA dependent DNA polymerase
4. A - RNA dependent DNA polymerase, B - DNA dependent RNA polymerase, C - RNA dependent RNA polymerase.

Q. Assertion :Extraction and purification of enzymes is laborious and expensive. Reason: Protein engineering can be used to produce enzymes at large scale.

1. Both the assertion and the reason are true and the reason is a correct explanation of the assertion.
2. Both the assertion and reason are true but the reason is not a correct explanation of the assertion.
3. The assertion is true but the reason is false.
4. Both the assertion and reason are false.

Q. The diagram below represents the 'Central Dogma' of molecular biology. Choose the correct combination of labeling.

1. A = Translation, B = DNA, C = Protein, D = Transcription, E = RNA
2. A = Protein, B = RNA, C = DNA, D = Translation, E = Transcription
3. A = DNA, B = RNA, C = Protein, D = Transcription, E = Translation
4. A = RNA, B = DNA, C = Protein, E = Transcription, D = Translation

Q. Read the given passage.

1. I only
2. III only
3. I and II only
4. II and III only
5. I, II, and III

Q. Find the odd one out with respect to central dogma.

Q. (a) Look at the above sequence and mention the events A, B, and C.
(b) What does Central Dogma state in molecular biology? How does it differ in some virus?

Q. The central dogma is not applicable in the case of

1. Retroviruses
2. All plant viruses
3. All animal viruses
4. All prokaryotes

Q. What do you mean by central dogma ?