Inheritance of Haemophilia

Q.

Which of the following is not a genetic disease in humans

1. Colour blindness

2. Sickle cell anaemia

3. Anaemia

4. Haemophilia

Q.

Name any two genetic diseases in humans.

Q.

Can males pass on haemophilia?

Q. Male (XY) or Female (XX), Which one is dominant and how to determine it?

Q.

Study the pedigree chart given below.

It shows that:

1. Inheritance of a recessive sex-linked disease like haemophilia.

2. Inheritance of a sex-linked disease like colour blindness.

3. Inheritance of a condition like phenylketonuria as on autosomal recessive trail.

4. The pedigree chart is wrong as this is not possible

Q.

What are the three types of haemophilia?

Q. Haemophilia is more commonly seen in human males than in human females because :

1. This disease is due to a Y - linked recessive mutation
2. This disease is due to an X - linked recessive mutation
3. This disease is due to an X - linked dominant mutation
4. A greater proportion of girls die in infancy

Q. Which of the following is congenital or inherited disease?

1. Haemophilia
2. Asthma
3. Pellagra
4. Arthritis

Q. Inheritance in which maternal characters are shown by male offspring and paternal by female is known as

1. Blending inheritance
2. Criss-cross inheritance
3. Alternative inheritance
4. Amphi-gonous inheritance

Q. What is the cause of haemophilia and colour blindness?

Q.

Skin has the ability to synthesize small quantities of vitamin __________________ on the exposure to sun.

Q. John, a male hemophiliac, marries Jane, a normal woman, and together they have four children, two boys (Mark and Mike) and two girls (Molly and Mary). None of the children display the symptoms of hemophilia. Mark, Mike, Molly, and Mary all marry normal individuals and have children. None of Mark's or Mike's children, male or female, display symptoms of hemophilia, but the sons of Molly and Mary all display symptoms of hemophilia while the daughters of Molly and Mary do not. Which of the following individuals are heterozygous for hemophilia?

1. John, Mark, and Mike
2. Mark, Mike, Molly, and Mary
3. John and Jane
4. Molly and Mary
5. Mark and Mike

Q.

Why is recessive trait found in fewer individuals?

Q. Study the pedigree chart given below

What does it show?

1. Inheritance of a condition like phenylketonuria as an autosomal recessive trait
2. Inheritance of a recessive sex-linked disease like haemophilia
3. The pedigree chart is wrong as this is not possible
4. Inheritance of a sex-linked inborn erro of metabolism like phenylketonuria

Q. The incorrect statement with regard to haemophilia is :

1. It is a sex linked disease
2. It is a recessive disease
3. It is dominant disease
4. A single protein involved in the clotting of blood is affected

Q. Which one of the following diseases in man belongs to the same category as haemophilia?

1. Hypermetropia
2. Night blindness
3. Rabies
4. Colour blindness

Q. Why do you think that more males are affected by sex-linked diseases?

Q. If a normal woman marries a colour blind man then

1. All their children will be colourblind.
2. All their sons will be colourblind but the daughters will be normal.
3. All sons and 50% of daughters are normal but 50% daughters will be colour blind.
4. All the children will be normal.
5. All daughters will be colourblind and sons will be normal.