Inheritance of Haemophilia

Q. A man whose father was colour blind and mother is normal marries a woman who had a colour blind mother and normal father. What percentage of male children of this couple will be colour blind?

1. 0%
2. 50%
3. 75%
4. 25%

Q.

A disease caused by an autosomal primary nondisjunction is

1. Downs syndrome

2. Klinefelter’s syndrome

3. Turner’s syndrome

4. Sickle cell anaemia

Q.

The production of gametes by the parents, the formation of zygotes, and the F1 and F2 plants, can be understood from a diagram called

1. Bullet square

2. Punch square

3. Net square

4. Punnett square

Q.

What gender does down syndrome affect most?

Q. In Drosophila melanogaster, white (w) and miniature (m) refer to the alleles controlling recessive traits for

1. body colour and eye colour
2. eye colour and body size
3. eye colour and wing size
4. wing size and body size

Q. Which of the following characteristics are seen in an individual with Down’s syndrome?

1. Short stature with small, round head
2. Palm crease and furrowed tongue
3. Retardation in physical, mental and psychomotor development
4. All of the above

Q.

Name two sex linked inherited diseases and write their causes.

Q.

Why do males only get haemophilia?

Q.

Which one of the following conditions of the zygotic cell would lead to the birth of a normal human female child?

1. Only one Y chromosome

2. Two X chromosomes

3. One X and one Y chromosome

4. Only one X chromosome

Q. Identify the mismatched pairs:
$\begin{array}{ccc}& \text{Disorder}& \text{Characteristic feature}\\ i.& \text{Haemophilia}& \text{Sex linked recessive}\\ ii.& \text{Down's syndrome}& \text{Trisomy 21}\\ iii.& \text{Turner's syndrome}& \text{Trisomy of sex chromosome}\\ iv.& \text{Klinefelter's syndrome}& \text{Monosomy of sex chromosome}\end{array}$

1. i, iii
2. ii, iv
3. i, ii
4. iii, iv

Q. Which one of the following is a protein deficiency disease?

1. night blindness
2. eczema
3. cirrhosis
4. kwashiorkor

Q. Haemophilia is more commonly seen in human males than in human females because :

1. This disease is due to a Y - linked recessive mutation
2. This disease is due to an X - linked recessive mutation
3. This disease is due to an X - linked dominant mutation
4. A greater proportion of girls die in infancy

Q.

Why is hemophilia called Christmas disease?

Q. Brown heart disease in Cauliflower is due the defiency of

1. Copper
2. Boron
3. Phosphorus
4. Iron

Q. Study the pedigree chart given below

What does it show?

1. Inheritance of a condition like phenylketonuria as an autosomal recessive trait
2. The pedigree chart is wrong as this is not possible
3. Inheritance of a sex-linked inborn erro of metabolism like phenylketonuria
4. Inheritance of a recessive sex-linked disease like haemophilia

Q. Which of the following diseases shows its transmission from unaffected carrier female to some of the male progeny?

1. Haemophilia
2. Myotonic dystrophy
3. Turner’s syndrome
4. Down’s syndrome

Q. Why is Haemophilia generally observed in human males?

Q. Christmas disease is another name for :

1. Haemophilia B
2. Hepatitis B
3. Down's syndrome
4. Sleeping sickness

Q.

How long is the average life span of a person with haemophilia?

Q.

What Is the Most Common Bleeding Disorder?

Q. Which of the following conditions is related to Haemophilia ?

1. A recessive gene responsible present in the X chromosome.
2. A dominant gene responsible present in the X chromosome.
3. A dominant gene responsible present in the Y chromosome.
4. A recessive gene responsible present in the autosomal chromosome.

Q.

Haemophilia is a type of:

1. Autosomal recessive disorder

2. X-linked dominant disorder

3. Autosomal dominant disorder

4. X-linked recessive disorder

Q. If both parents are carriers for thalassaemia, which is autosomal recessive disorder, what are the chances of pregnancy resulting in an affected child?

1. 25%
2. 100%
3. No chance
4. 50%

Q. A woman heterozygous for haemophilia marries a haemophilic man. Choose the correct options with the ratios of carrier daughter, haemophilic daughter, normal son and haemophilic son.

1. 1: 2: 2:1
2. 1:1:1:1
3. 2:1:1:2
4. 2:1:1:1

Q. A normal-visioned man whose father was colourblind, marries a woman whose father was also colourblind. They have their first child as a daughter. What are the chances that this child would be colourblind?

1. 100%
2. 0%
3. 25%
4. 50%

Q. It was explained that only males are affected by haemophilia because they do not have an extra normal X chromosome to compensate for the defective one.but won't the disease be transferred to daughter too if father is affected and mother is a carrier?

Q.

State one visible effect of:

Addisons disease

Q. Choose the correct pairs from the following.
A. Haemophilia - X- linked genetic disorder
B. An extra one chromosome seen along with diploid number of chromosomes
C. Holandric genes - Y- linked gene characters seen only in males
D. Sickle cell anaemia - Heterozygous and autosomal realated

1. A, B and C
2. A, C and D
3. B, C and D
4. A, B and D

Q. Which of the following diseases is hereditary?

1. Cancer
2. Tuberculosis
3. Haemophilia
4. Dysentery

Q. Scurvy is caused due to deficiency of vitamin

1. B
2. C
3. A
4. E