The Immune System

Q.

Most abundant immunoglobulin is

1. IgA

2. IgE

3. IgG

4. IgM

Q. The exaggerated response of the immune system to certain antigens is called

1. allergy
2. inflammation
3. infection
4. auto-immunity

Q. The immune system plays an important role in:
$a$. Recognition of foreign antigens
$b$. Responds to antigens and remembers them
$c$. Allergic reactions
$d$. Auto-immune diseases
$e$. Organ transplantation

1. $b,c$ and $e$
2. $a$ and $b$ only
3. $a,b,c$ and $d$
4. $a,b,c,d$ and $e$

Q.

Write the noun form of treat

Q.

Which cell secretes antibody?

1. Neutrophils

2. Lymphocytes

3. Eosinophils

4. Monocytes

Q. In higher vertebrates, the immune system can distinguish self- cells and foreign organisms. If this property is lost due to genetic abnormality and it attacks self-cells, then it leads to _______.

1. autoimmune disease
2. active immunity
3. allergic response
4. passive immunity

Q. In which one of the following options the two examples are correctly matched with their particular type of immunity?

1. Examples - Anti-tetanus and anti-snake bite injections
   Type of immunity - Active immunity
2. Examples - Mucus coating of epithelium lining the urinogenital tract and the HCl in stomach
   Type of immunity - Physiological barriers
3. Examples - Saliva in mouth and tears in eyes
   Type of immunity - Physical barriers
4. Examples - Polymorphonuclear leukocytes and monocytes
   Type of immunity - Cellular barriers

Q. Which of the following statements is true regarding adaptive immunity?

1. Prior exposure to antigen is essential
2. Prior exposure to antigen is not essential
3. It is a non-specific defence mechanism
4. Macrophages are the major cells involved

Q.

How does the human body produce antibodies?

Q. To which type of barrier under innate immunity do saliva in mouth and tears from eyes belong?

1. Physical barriers
2. Cellular barriers
3. Cytokine barriers
4. Physiological barriers

Q. What is innate immunity? Mention any two types of innate immunity barriers.

Q.

The function of IgE is

1. Stimulation of complement system, passive immunity to foetus

2. Protection from inhaled/ingested pathogens

3. Mediate in allergic response

4. Activation of B-cells

Q.

What is the immune system?

Q.

Differentiate the following and give examples of each:

(a) Innate and acquired immunity

(b) Active and passive immunity

Q.

An antibody is

1. molecule that specifically inactivates an antigen

2. WBC which invades bacteria

3. secretion of mammalian RBC

4. component of blood

Q. Immunity acquired after an infection is

Q. Match column I with column II and identify the correct option from given below.

1. A - 2, B - 3, C - 4 and D - 1
2. A - 3, B - 1, C - 4 and D - 2
3. A - 4, B - 3, C - 2 and D - 1
4. A - 2, B - 4, C - 1 and D - 2

Q. The treatment of snake bite by antivenom is an example of

1. Artificially acquired passive immunity
2. Naturally acquired active immunity
3. Artificially acquired active immunity
4. Naturally acquired passive immunity

Q.

Which blood cells deal with the immune reactions?

Q. A heavily bleeding and bruised road accident victim was brought to a nursing home. The doctor immediately gave him an injection to protect him against a deadly disease.
(a) Write what did the doctor inject into the patient's body.
(b) How do you think this injection would protect the patient against the disease?
(c) Name the disease against which this injection was given and the kind of immunity it provides. [3]

Q. In hybridoma technology.

1. B-cells are fused with myeloma cells
2. T-cells are fused with myeloma cells
3. B-cells are fused with T-cells
4. None of the above

Q.

Are neutrophils B or T cells?

Q. Read the following statements and select the correct option.
(A) Thymosins plays a major role in differentiation of T lymphocyte which provides cell-mediated immunity.
(B) Thymosins promote the production of antibodies to provide humoral immunity.

1. Both (A) and (B) are true
2. (A) is false but (B) is true
3. Both (A) and (B) are false
4. (A) is true but (B) is false

Q. A condition that occurs when the immune system mistakenly attacks and destroys healthy body tissue is called

1. auto-immunity
2. immunization
3. allergy
4. immunodeficiency

Q. Write short notes on B-cells.

Q.

Surgical removal of thymus of a new born shall result in failure to produce

1. Monocytes

2. B-lymphocytes

3. Basophils

4. T-lymphocytes

Q. Read the following statements (1 - 2) and select the correct option.

Statement 1: B-cells are capable of binding soluble antigens while T-cells are not.
Statement 2 : The B-cells derived its letter designation from its site of maturation in birds, the bursa of Fabricius.

1. Both the statements 1 and 2 are correct
2. Statement 1 is correct and statement 2 is incorrect
3. Statement 2 is correct and statement 1 is incorrect
4. Both the statements 1 and 2 are incorrect

Q. Differentiate between the following with examples:
(a) Innate and acquired immunity
(b) Active and passive immunity

Q. A lymphocytes is most likely to encounter it's specific antigen when it is in the
1.bone marrow
2.spleen
3.thymus
4.cardiac muscle

Q. Acquired or adaptive immunity is the immunity that body acquires or gains over time. Which of the following mentioned statement is a feature of acquired immunity?

1. It remembers each and every immunological encounter of the body
2. Acquired immunity is pathogen-specific.
3. Can discriminate self and non-self cells
4. All of the above