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B
A base deletion only.
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C
A base substitution only.
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D
Either an insertion or a deletion of a base.
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Solution
The correct option is B Either an insertion or a deletion of a base. The sequence of three nucleotides of either DNA or RNA is known as a codon. The gene expression is performed by codons either by insertion or deletion of a base which can change the reading frame of sequence.hence the frameshift mutation occurs.
So the correct answer is 'Either an insertion or a deletion of a base'.