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Question
A functional complex comprising a cluster of genes including structural gene, a promoter gene, an operator gene and a regulator gene was discovered by:
A functional complex comprising a cluster of genes including structural gene, a promoter gene, an operator gene and a regulator gene was discovered by:
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Solution
The correct option is C Jacob and Monod
The operon model of prokaryotic gene regulation was proposed by Francois Jacob and Jacques Monod. They first explained the mechanisms of regulation of expression of genes responsible for coding the involved enzymes while working on an inducible system for the synthesis of a β-galactosidase enzyme in E. coli. For example, the lac operon consists of 3 structural genes, and a promoter, a terminator, regulator, and an operator. The three structural genes are z, y and a. The operator gene regulates the expression of structural genes by providing a binding site to the transcription factor which in turn regulate the gene expression by altering the binding of RNA polymerase to the promoter region. The regulator genes code for transcription factor/repressor proteins that bind to operators or promoters and prevent RNA polymerase from transcribing RNA.
Watson and Crick proposed the double-helix structure of DNA, the molecule containing human genes.
The one gene, one enzyme hypothesis is the idea proposed by Beadle and Tatum.
The Britten–Davidson model, also known as the gene-battery model, is a hypothesis for the regulation of protein synthesis in eukaryotes.
The operon model of prokaryotic gene regulation was proposed by Francois Jacob and Jacques Monod. They first explained the mechanisms of regulation of expression of genes responsible for coding the involved enzymes while working on an inducible system for the synthesis of a β-galactosidase enzyme in E. coli. For example, the lac operon consists of 3 structural genes, and a promoter, a terminator, regulator, and an operator. The three structural genes are z, y and a. The operator gene regulates the expression of structural genes by providing a binding site to the transcription factor which in turn regulate the gene expression by altering the binding of RNA polymerase to the promoter region. The regulator genes code for transcription factor/repressor proteins that bind to operators or promoters and prevent RNA polymerase from transcribing RNA.
Watson and Crick proposed the double-helix structure of DNA, the molecule containing human genes.
The one gene, one enzyme hypothesis is the idea proposed by Beadle and Tatum.
The Britten–Davidson model, also known as the gene-battery model, is a hypothesis for the regulation of protein synthesis in eukaryotes.
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