Question

A gorilla like man with huge hand and legs. This is due to the abnormal secretion of

• A. Pituitary FSH
• B. Pituitary LH
• C. Pituitary GH
• D. Thyroid

Answer 1

The correct option is C Pituitary GH

Follicle stimulating hormone (FSH) promotes spermatogenesis in seminiferous tubules of male and follicle development in females. Its abnormal secretion affects the gamete formation. Option A is incorrect. LH is also gonadotropin and stimulates production of sex hormones by gonads; its abnormal secretion affect the production of see hormones, not growth, hence option B is incorrect. GH is the growth hormone, secreted by anterior pituitary, which targets soft tissues and bones and serves to stimulate cell division, protein synthesis and bone growth. Overproduction of GH in adults causes acromegaly, characterized by enlargement of feet, hands and face (specially the chin, nose and eyebrows ridges) as long bones do not respond to the hormone in them. Thus, option C is correct. Thyroid hormones target the metabolic rate, not growth of the body. Abnormal secretion of thyroid causes cretinism (hypothyroidism) and Graves disease (hyperthyroidism) which makes option D incorrect. Thus, the correct answer is C.