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Question

a) How drugs can be classified according to different criteria? Write the name of each?
b) How anti histamines work? Give an example of any anti histamine?
c) Write the structural formula of any sleep producing barbiturate?

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Solution

a) Drugs can be classified according to following different criteria.
(i) Classification based on pharmacological effects of the drugs:
Analgesics, antacids, tranquilizers, antibiotics and antiseptics.
(ii) Classification based on action of drugs on a particular biochemical process:
Painkillers, antiarthritis medicines, local anaesthetic agents, etc.
(iii) Classification based on chemical structure:
Alcohols, ketones, hydrocarbons, esters, amides, lactones, phenols, etc.
(iv) Classification based on molecular targets:
Target biomolecules include carbohydrates, proteins, nucleic acids
b) Histamine in the stomach stimulates the secretion of hydrochloric acid and pepsin. Antihistamines prevent the interaction between histamine and receptors in the stomach wall, releasing less amount of acid. Histamine contracts smooth muscles and relaxes other muscles of blood vessels of stomach walls, it is a potent vasodilator. Examples of Antihistamines include ranitidine, cimetidine, terfenadine (Seldane), brompheniramine (Dimetapp) etc.
c) The structural formula of sleep producing barbiturate Luminal is as shown in the image.

630552_602784_ans_f239a3ed217b439b9ff3cb0d663fd3fc.png

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