(A) Large reductions in the ozone layer, which sits about 15-30 km above the Earth, take place each winter over the polar regions, especially the Antarctic, as low temperatures allow the formation of stratospheric clouds that assist chemical reactions breaking down ozone. (B) Industrial chemicals containing chlorine and bromine have been blamed for thinning the layer because they attack the ozone molecules, making them to break apart. (C) Many an offending chemicals have now been banned. (D) It will still take several decades before these substances have disappeared from the atmosphere
Statement (A) is grammatically correct. Statement (D) does not have any mistake either. Statement (C) is incorrect because of the wrong usage of the adjective 'offending' with chemicals. Moreover, when "an" is used, "chemical" and not "chemicals" should be used.
In Statement (B) "making them to break apart" is wrong usage
Thus answer option (c) is the right answer choice.