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Question

A mutation changes the original base sequence of DNA, GATAGCCG to a new sequence GGTAGCCG. What is the type of mutation?

A
Transition
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B
Transversion
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C
Translocation
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D
Inversion
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Solution

The correct option is A Transition
Transition, in genetics and molecular biology, refers to a point mutation that changes a purine nucleotide to another purine (A ↔ G), or a pyrimidine nucleotide to another pyrimidine (C ↔ T).
In the two sequences given in the question, A (adenine, a purine) at position 2 has been replaced with G (guanine, a purine).
So, the correct answer is 'Transition'.

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