Question

Original DNA sequence: $ATGGA-AGC$
New DNA sequence: $ATTGACAGC$

Select the correct type of mutation.
I. Point mutation
II. Deletion
III. Frameshift

• A. I only
• B. II only
• C. III only
• D. I and II
• E. I and III

Answer 1

The correct option is C III only

Mutation in single nucleotide base of a DNA segment is called as a point mutation. Deletion refers to the removal of one or more nucleotides from the DNA molecule. The gene mutations that alter the base sequence of a whole genetic frame from the point of the mutation are called frame shift mutations. it includes addition or deletion of one or more nucleotides. Given mutated DNA sequence has one substitution and one insertion mutation causing shifting of reading frame of base sequence i.e. frameshift mutation. Thus, the correct answer is option C.