Question

A mutation resulting in no change in the amino acid sequence of a protein is classified as

• A. Frameshift mutation
• B. Inversion mutation
• C. Silent mutation
• D. Deletion mutation
• E. Translocation mutation

Answer 1

The correct option is C Silent mutation

A. In Frameshift mutation, there occurs a deletion or insertions of one or more nitrogenous bases and this results in a shift in reading frame either backward or forward.

B. In inversion mutation, a section of chromosome becomes changed after rotation through 180°.

C. Silent mutation is any gene mutation which does not result in phenotypic expression. As more than one codon specify same amino acid (due to degeneracy of code), the change in codon may not result into alteration in amino acid.

D. In deletion mutation, there is removal of one or more nitrogenous bases from a nucleotide chain.

E. In translocation mutation, there is a kind of rearrangement in which a block of genes from one chromosome are transferred to other non-homologous chromosome.

Hence a mutation resulting in no change in the amino acid sequence of a protein is silent mutation.

So, the correct answer is 'Silent mutation'.