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Question

Which of the following mutations produces no change in the sequence of protein?

A
Point mutation
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B
Frameshift mutation
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C
Insertion
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D
Deletion
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E
Stop mutation
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Solution

The correct option is A Point mutation
Mutation refers to the changes in the nucleotide sequence of DNA. Mutations are classified on the basis of their effect on DNA nucleotide. While some mutations affect large sections of DNA, others affect only certain points along the DNA strand. These small, specific mutations are called point mutations. Functionally point mutations are categorized as non-sense, missense, and silent mutations. Of these silent mutations code for the same amino acid and hence these mutations leaves no effect on the functioning and sequence of the protein. Thus, the correct answer is option A.

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