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Question

A person suffering from a disease caused by Plasmodium, experiences recurring chill and fever at the time when ?

A
The trophozoites reach maximum growth and give out certain toxins
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B
the parasite after its rapid multiplication inside RBCs ruptures them, releasing the stage to enter fresh RBCs
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C
the microgametocytes and megagametocytes are being destroyed by the WBCs
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D
the sporozoites released from RBCs are being rapidly killed and broken down inside spleen.
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Solution

The correct option is B the parasite after its rapid multiplication inside RBCs ruptures them, releasing the stage to enter fresh RBCs
In malaria, chill and fever are due to the release of a toxic substance haemozoin, formed by the breakdown of haemoglobin present in RBCs. It will be released after the rupture of RBCs in erythrocytic schizogony.

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