Question

A person with 'O' blood group has both antibodies A and B. So consider a situation in which a person with blood group 'O' donates his blood to a person with blood group 'A'. So that antibody A of blood group 'O' should react with antigen A of blood group 'A', so this should lead to coagulation of blood, but this isn't taking place, why?

Answer 1

A person with 'O' blood group has both antibodies A and B, in a blood transfusion case where a person with 'A' blood group receives blood from 'O' blood group, the plasma of blood group 'O' contains antibodies for antigen 'A', but agglutination or coagulation does not occur due to very few number of donor antibodies.