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Question
A substance that is unrelated to a substrate and reversibly changes the activity of an enzyme is known as
A substance that is unrelated to a substrate and reversibly changes the activity of an enzyme is known as
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Solution
The correct option is C Allosteric modulator
Enzymatic reactions inside the cells control the functionality of it and hence, regulation of enzyme activity is of utmost importance for cell sustenance. One way of regulating an enzyme is via allosteric regulation. Allosteric regulation of an enzyme is achieved when a modulator binds to the enzyme at a site different from its substrate binding site and brings about a transient (reversible) conformational change in the enzyme structure so as to affect its substrate binding efficiency, hence modulating its catalytic activity. Many of our metabolic pathway enzyme are controlled by allosteric interactions. For example, in a feedback inhibition system of a metabolic pathway, sometimes the end product acts as an allosteric inhibitor of an enzyme which comes early in the pathway, thereby passing the signal to check the pathway when the required threshold of products is reached. The modulator (end product of the pathway) binds momentarily to the enzyme, depending on its cellular concentration. So, the correct answer is 'Allosteric modulator'.
Enzymatic reactions inside the cells control the functionality of it and hence, regulation of enzyme activity is of utmost importance for cell sustenance. One way of regulating an enzyme is via allosteric regulation. Allosteric regulation of an enzyme is achieved when a modulator binds to the enzyme at a site different from its substrate binding site and brings about a transient (reversible) conformational change in the enzyme structure so as to affect its substrate binding efficiency, hence modulating its catalytic activity. Many of our metabolic pathway enzyme are controlled by allosteric interactions. For example, in a feedback inhibition system of a metabolic pathway, sometimes the end product acts as an allosteric inhibitor of an enzyme which comes early in the pathway, thereby passing the signal to check the pathway when the required threshold of products is reached. The modulator (end product of the pathway) binds momentarily to the enzyme, depending on its cellular concentration. So, the correct answer is 'Allosteric modulator'.
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