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Question

A woman with an Albinic father marries an albinic man. The proportion of her progeny (normal and albino) will be ?

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Solution

Albinism is an autosomal recessive metabolic disorder. It is characterized by the complete or partial absence of the skin, hair, and eyes due to the absence or defect of tyrosinase, copper-containing enzyme involved in the presence of melanin. An albino man (rr) marries a normal woman will have a progeny carrying one recessive allele and one normal in a heterozygous(rR). Thus, his daughter will be with Rr genes. The proportion of the progeny will be 1:1.

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