Question

According to the accepted concept of hormone action, if receptor molecules are removed from target organs, then the target organ will _____.

• A. Continue to respond to the hormone without any difference
• B. Not respond to the hormone
• C. Continue to respond to the hormone but will require higher concentration
• D. Continue to respond to the hormone but in the opposite way.

Answer 1

The correct option is B

Not respond to the hormone

The hormones that are amino acid derivatives, peptides and proteins are large and insoluble in lipids, and cannot enter the target cell. Therefore, they act at the cell surface. They bind to specific receptor molecules located on the surface of the cell membrane. Therefore, if receptor molecules are removed from target organs, then the target organ will not respond to the hormone.