Question

All of the following take place in lock and key model except

• A. The substrate binds to the active site.
• B. The enzyme lowers the activation energy of the reaction.
• C. The enzyme is changed by the substrate.
• D. The substrate is chemically changed by the enzyme.
• E. The enzyme is altered by the reaction

Answer 1

The correct option is C The enzyme is changed by the substrate.

Lock and key model was proposed as an analogy to the action of specific enzyme with a single substrate. In this model, the substrate attaches on the active site of the enzyme to form an enzyme substrate complex, which further turns to product. According to this theory, the substrate donot change the shape of active site on the enzyme.

So, the correct answer is option C.