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Question

Alloxan treatment destroys:


A

Leydig cells

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B

STH cells

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C

β-cells of islets of Langerhans

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D

Sertoli cells

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Solution

The correct option is C

β-cells of islets of Langerhans


The correct option is C.

Explanation of correct option:

  1. Alloxan is a toxic analog of glucose that destroys insulin-producing cells of the pancreas.
  2. These cells are β-cells of islets of Langerhans.
  3. Insulin is secreted by the β-cells of islets of Langerhans that are components of the pancreas and regulates blood glucose levels.

Explanation of incorrect options:

Option A:

  1. Leydig cells are present in the testes and help in secretion of androgens.
  2. Alloxan treatment does not affect Leydig cells.

Option B:

  1. STH or the somatotropin hormone stimulates the growth and metabolism of carbohydrates, proteins, and fats.
  2. Alloxan treatment does not affect STH cells.

Option D:

  1. Sertoli cells help in spermatogenesis by providing nourishment to the developing sperms.
  2. Alloxan treatment does not affect Sertoli cells.

Final answer: Alloxan treatment causes destruction of β-cells of islets of Langerhans.


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