Question

Alloxan treatment destroys:

• A. Leydig cells
• B. STH cells
• C. β-cells of islets of Langerhans
• D. Sertoli cells

Answer 1

The correct option is C

β-cells of islets of Langerhans

The correct option is C.

Explanation of correct option:

1. Alloxan is a toxic analog of glucose that destroys insulin-producing cells of the pancreas.
2. These cells are β-cells of islets of Langerhans.
3. Insulin is secreted by the β-cells of islets of Langerhans that are components of the pancreas and regulates blood glucose levels.

Explanation of incorrect options:

Option A:

1. Leydig cells are present in the testes and help in secretion of androgens.
2. Alloxan treatment does not affect Leydig cells.

Option B:

1. STH or the somatotropin hormone stimulates the growth and metabolism of carbohydrates, proteins, and fats.
2. Alloxan treatment does not affect STH cells.

Option D:

1. Sertoli cells help in spermatogenesis by providing nourishment to the developing sperms.
2. Alloxan treatment does not affect Sertoli cells.

Final answer: Alloxan treatment causes destruction of β-cells of islets of Langerhans.