Question

An enzymes which does not helps in the replication of DNA is

• A. DNA polymerase
• B. DNA ligase
• C. DNA topoisomerase
• D. DNA primase
• E. DNA methyltransferase

Answer 1

The correct option is E DNA methyltransferase

DNA polymerase helps in DNA dependent DNA synthesis i.e. replication. It is an enzyme that synthesis DNA molecules from deoxyribonucleotides, the building blocks of DNA.

DNA ligase helps in joining of Okazaki fragments together by catalyzing the formation of the phosphodiester bond. These fragments are formed in the lagging strand of DNA duplex.

DNA topoisomerase that helps in the overwinding or unwinding of DNA. It introduces negative and positive coils in the DNA during its replication process.

DNA primase is involved during replication to catalyze the synthesis of a short RNA segment complementary to a ssDNA template. It is a type of RNA polymerase.

DNA methyltransferase catalyzes the transfer of a methyl group to DNA.

So, the correct answer is 'DNA methyltransferase'