An example of competitive inhibition of an enzyme is the inhibition of
A
Succinic dehydrogenase by malonic acid
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B
Cytochrome oxidase by cyanide
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C
Hexokinase by glucose -6- phosphated
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D
Carbonic anhydrase by carbon dioxide
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Solution
The correct option is A Succinic dehydrogenase by malonic acid
Inhibitors, resemble with substrate molecules, join in the active site of the enzyme and inhibit the enzyme activity are called Competitive enzyme inhibitors.
Malonate is a competitive inhibitor of succinic dehydrogenase. The binding of succinic dehydrogenase to the substrate, succinate, is completely inhibited. Succinic dehydrogenase catalyzes the oxidation of succinate to fumarate in the Kreb cycle was an experiment demonstrated as an example of competitive inhibition.
So, the correct option is, 'succinic dehydrogenase by malonic acid'