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Question
Anaphase-promoting complex(APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur?
Anaphase-promoting complex(APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur?
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Solution
The correct option is B Chromosomes will not segregate
Anaphase-promoting complex ( APC ) is one of ubiquitin ligases, which plays a key role in the cell cycle. It is found in the nucleus of interphase cells, and that spreads throughout the cytoplasm and associate with parts of the spindle apparatus during mitosis. Without APC, cells cannot separate their sister chromatids in anaphase, they cannot exit from mitosis and divide into two daughter cells
Anaphase-promoting complex ( APC ) is one of ubiquitin ligases, which plays a key role in the cell cycle. It is found in the nucleus of interphase cells, and that spreads throughout the cytoplasm and associate with parts of the spindle apparatus during mitosis. Without APC, cells cannot separate their sister chromatids in anaphase, they cannot exit from mitosis and divide into two daughter cells
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