Question

Aneuploidy of which chromosome causes Patau syndrome?

• A. ${13}^{th}$
• B. ${21}^{st}$
• C. ${14}^{th}$
• D. ${18}^{th}$

Answer 1

The correct option is A ${13}^{th}$

Patau syndrome is a chromosomal abnormality in which cells have an extra chromosome number 13 (45A+XX/XY). This extra genetic material disrupts normal development and causes multiple and complex organs defects.

Down syndrome is caused due to trisomy of ${21}^{\mathrm{st}}$ chromosome. Edwards syndrome caused by the trisomy of ${18}^{\mathrm{th}}$ chromosome.