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Question

Another name of antibiotic mycophenolic acid that cannot attack Mycoplasma is

A
Tetracycline
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B
Streptomycin
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C
Penicillin
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D
Chloramphenicol
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Solution

The correct option is B Penicillin
The antibiotics tetracycline, streptomycin and chloramphenicol inhibit protein synthesis while the antibiotic penicillin inhibits cell wall synthesis.
Tetracycline binds to the 30S ribosomal subunit and interferes with aminoacyl-tRNA binding.
Streptomycin binds with the 30S subunit of the bacterial ribosome and causes misreading of the mRNA.
Chloramphenicol binds to the 50S ribosomal subunit and blocks the formation of the peptide bond by inhibiting the enzyme peptidyl transferase.
Penicillin inhibits peptidoglycan synthesis in bacteria. It inhibits the transpeptidation enzymes which are involved in cross-linking during peptidoglycan formation thereby inhibiting cell wall formation.
Since Mycoplasma is the smallest bacteria lacking a cell wall, it won't be affected by the antibiotic penicillin. As mycophenolic acid is also extracted from Penicillium thus, also called as penicillin.
So, the correct answer is C.

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