Question

Antibiotic inhibiting interaction between tRNA and mRNA during protein synthesis in bacteria

• A.
  Erythromycin
• B.
  Streptomycin
• C.
  Neomycin
• D.
  Tetracycline

Answer 1

The correct option is C

Neomycin
Tetracycline
Tetracycline acts by inhibiting the binding of aminoacyl tRNA to ribosomes.

Neomycin
Neomycin irreversibly binds to the 30S subunit of the ribosome, thus inhibiting the interaction between tRNA and mRNA. This will lead to inhibition of translation.

Erythromycin
Erythromycin acts by inhibiting the aminoacyl translocation along the ribosomes.

Streptomycin
Streptomycin acts by inhibiting the initiation of translation and also causes misreading of the codon.