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Antigen presenting cells
Antigen presenting cells
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Solution
The correct option is A activates T cells
Macrophages, dendritic cells and lymphocytes are together called antigen presenting cells (APCs). They are called so because they have the ability to present antigen on their surface with the help of a protein complex called major histocompatibility complex or MHC.
MHC is a protein complex present on all cells of the body. Whenever T cells come close to any cell they check for the peptide or MHC which helps them to differentiate between self or non self.
Macrophages, dendritic cells engulf pathogens and present a part of the pathogen called antigen on their surface or on its MHC. The antigen presenting cells move to the lymph node. Once they enter inside the lymph node, naive T cells recognize the antigen (as non-self) being presented by the macrophages or dendritic cells.
The naive T cells get activated and proliferate to form Cytotoxic T cells, Memory T cells and Helper T cells.
Cytotoxic T cells are also called killer cells as they are capable of killing both pathogens and cells that are infected with pathogens by releasing pore/hole forming proteins called the perforins that punch holes in the cells and kill them.
Thus APCs activates T cells to evoke immune response, but is not involved in directly fighting and killing the pathogen.
Macrophages, dendritic cells and lymphocytes are together called antigen presenting cells (APCs). They are called so because they have the ability to present antigen on their surface with the help of a protein complex called major histocompatibility complex or MHC.
MHC is a protein complex present on all cells of the body. Whenever T cells come close to any cell they check for the peptide or MHC which helps them to differentiate between self or non self.
Macrophages, dendritic cells engulf pathogens and present a part of the pathogen called antigen on their surface or on its MHC. The antigen presenting cells move to the lymph node. Once they enter inside the lymph node, naive T cells recognize the antigen (as non-self) being presented by the macrophages or dendritic cells.
The naive T cells get activated and proliferate to form Cytotoxic T cells, Memory T cells and Helper T cells.
Cytotoxic T cells are also called killer cells as they are capable of killing both pathogens and cells that are infected with pathogens by releasing pore/hole forming proteins called the perforins that punch holes in the cells and kill them.
Thus APCs activates T cells to evoke immune response, but is not involved in directly fighting and killing the pathogen.
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