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Question

Antisense RNA is complementary to which of the following?


A
rRNA
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B
tRNA
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C
mRNA
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D
snRNA
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Solution

The correct option is C mRNA
Antisense RNA is a single-stranded RNA that is complementary to messenger RNA (mRNA) strand transcribed within a cell.
Antisense RNA is introduced into a cell to inhibit translation of a functional mRNA by complementary base pairing with it and physically interfering it from its translation machinery.
When the complementary sense and antisense RNA are present in the cytoplasm of the same cell, they form a stable duplex dsRNA and subsequently interferes with the gene expression or protein synthesis process by deactivating the mRNA.

rRNA is a ribozyme that carries out the process of protein synthesis in ribosomes, it is a non-coding type of RNA which is essential for every cell's gene expression, comprising approximately 80% of the total RNAs in a rapidly growing cell.

tRNA is a type of RNA molecule which reads the mRNA and decodes the message carried by it into a protein sequence with the help of its nucleotide sequence. It recognizes the codon and transfers the appropriate amino acids to the growing chain of the peptide.

Small nuclear RNA (snRNA) is a class of small RNA molecules that are found within splicing speckles (subnuclear structure enriched in pre-mRNA factors in the interchromatin structure), and Cajal bodies (small spherical bodies found in the nucleus of actively dividing cells like embryonic cells and tumor cells, or metabolically active cells like neurons). snRNA participates in the pre-mRNA splicing reaction as a small nucleoprotein complex, which includes a single spliceosomal snRNA complex with a number of proteins. Removal of intervening sequences, introns from pre-mRNA is of fundamental importance to gene expression in eukaryotes.

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BIOLOGY
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