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Question
Arrange the following sentences in sequential order.
a) Antigen gets broken down into smaller fragments.
b) An antigen is internalised by phagocytosis.
c) An antigen is attracted by chemotaxis and attaches to the cell surface.
d) Antigen fragments binds to the MHC I and MHC II and gets transported to the membrane.
Arrange the following sentences in sequential order.
a) Antigen gets broken down into smaller fragments.
b) An antigen is internalised by phagocytosis.
c) An antigen is attracted by chemotaxis and attaches to the cell surface.
d) Antigen fragments binds to the MHC I and MHC II and gets transported to the membrane.
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Solution
The correct option is A c, b, a, d
An antigen is attracted by chemotaxis and attaches to the cell surface of antigen-presenting cells, such as B-cells, dendritic cells and macrophages. This is followed by antigen processing that includes protein fragmentation (proteolysis) followed by its internalization. Then the antigen is phagocytosed. Its peptide fragments gets transported to the membrane and are expressed as peptide-MHC complex at the cell surface where they can be recognized by the T cell receptor ( TCR ) on a T cell. There are two classes of MHC proteins, MHC class I and MHC class II. So, the correct answer is ' c,b,a,d'
An antigen is attracted by chemotaxis and attaches to the cell surface of antigen-presenting cells, such as B-cells, dendritic cells and macrophages. This is followed by antigen processing that includes protein fragmentation (proteolysis) followed by its internalization. Then the antigen is phagocytosed. Its peptide fragments gets transported to the membrane and are expressed as peptide-MHC complex at the cell surface where they can be recognized by the T cell receptor ( TCR ) on a T cell. There are two classes of MHC proteins, MHC class I and MHC class II.
So, the correct answer is ' c,b,a,d'
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