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Question

Assertion :5-bromouracil can cause mutations. Reason: It is called as base analogue.

A
Both Assertion and Reason are correct and Reason is the correct explanation for Assertion.
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B
Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion.
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C
Assertion is correct but Reason is incorrect.
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D
Both Assertion and Reason are incorrect.
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Solution

The correct option is A Both Assertion and Reason are correct and Reason is the correct explanation for Assertion.
5-bromouracil is a base analogue of thymine. It has a bromine at the site of 5th carbon where there is CH3in thymine. The keto form can undergo complementary base pairing with adenine and the enol form undergoes complementary base pairing with guanine. This results in DNA mutation. Thus the correct answer is option A.
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