Assertion :A piece of DNA inserted into an alien organism generally does not replicate if not inserted into a chromosome. Reason: Chromosomes have specific sequences called 'ori' region where DNA replication is initiated.

Both Assertion and Reason are correct and Reason is the correct explanation for Assertion

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Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion

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Assertion is correct but Reason is incorrect

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Both Assertion and Reason are incorrect

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Solution

The correct option is A Both Assertion and Reason are correct and Reason is the correct explanation for Assertion
'Origin of replication' is a sequence from where replication starts by binding of polymerase enzyme.
An isolated piece of DNA without the origin of replication or 'ori' site cannot replicate and is gradually lost during nuclear divisions.
But if it is inserted within a chromosome it is replicated along with the chromosome as a result of the replication process initiated by the 'origin of the replication site of the chromosome.
This is the reason why recombinant vectors used in genetic engineering must contain an origin of replication so that they can replicate themselves during cell division in order to ensure the presence of the recombinant genes in all the progeny.
So, the correct answer is option A.

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