Assertion and Reason
In the following questions a statement of assertion (A) followed by a statement reason (R) is given. Choose the correct answer out of the following choice..
(a) Assertion and reason both are correct statements but reason does not explain assertion.
(b) Assertion and reason both are correct and reason explains asssWon.
(c) Both assertion and reason are Wrong statements.
(d) Assertion is correct statement reason is wrong statement.
(e) Assertion is wrong statement reason is correct statement.
Assertion (A) Enzymes have active sites that hold substrate molecule for a chemical reaction.
Reason (R) Drugs compete with natural substrate by attaching covalently to the active site of enzyme.
Answer (d). The assertion is correct statement reason is the wrong statement
Correct reason: Drug competes with the natural substrate by attaching by weak bonds such as hydrogen bond, van der Weals', interaction and ionic bonding etc., to the active site of the enzyme.