Question

Assertion: Competitive inhibitors compete with natural substrate for their attachment on the active sites of enzymes.

Reason: In competitive inhibition, inhibitor binds to the allosteric site of the enzyme.

• A. Assertion is correct statement reason is wrong statement
• B. Assertion is wrong statement reason is correct statement
• C. Assertion and reason both are correct, and reason explains the assertion
• D. Assertion and reason both are correct statement, but reason does not explain assertion
• E. Both assertion and reason are wrong statements

Answer 1

The correct option is A Assertion is correct statement reason is wrong statement

Assertion

⮚ Competitive inhibitors (drugs) compete with the natural substrates for their attachment to the active sites of enzymes.

⮚ These kinds of drugs block the active site of the enzyme & prevent the linkage between enzyme & substrate inhibiting the natural catalytic activity of the enzyme.

So, assertion is correct.

Reason

⮚ In competitive inhibition, the inhibitor binds to the active site of the enzyme.

⮚ In non-competitive inhibition, the inhibitors (different from competitive drugs) bind to a different site than the active site which is called the allosteric site of an enzyme.



So, reason is wrong.

Hence, assertion is correct statement, reason is wrong statement.