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Question

Assertion :Glycolysis is the first step of respiration in which glucose completely breaks into CO2 and H2O. Reason: In this process, there is net gain of twenty four molecules of ATP.

A
Both Assertion and Reason are correct and Reason is the correct explanation for Assertion.
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B
Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion.
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C
Assertion is correct but Reason is incorrect.
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D
Both Assertion and Reason are incorrect.
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Solution

The correct option is D Both Assertion and Reason are incorrect.
Glycolysis is the process of breakdown of glucose or similar hexose sugar into two molecules of pyruvic acid through a series of enzyme mediated reactions, releasing energy (ATP) and reducing power (NADH2). It is the first step of respiration, which occurs inside the cytoplasm and is independent of O2. In glycolysis, two molecules of ATP are consumed during double phosphorylation of glucose to form fructose 1,6 diphosphate. Four molecules of ATP are produced in the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate and phosphoenolpyruvate to pyruvate whereas, two molecules of NADH2 are formed during oxidation of glyceraldehyde 3-phosphate to 1,3-diphosphoglycerate. Since, each NADH is equivalent to 3 ATP, so net gain in glycolysis is 8 ATP.

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