Question

Assertion : SCID is a primary immunodeficiency.

Reason : It is a serious congenital immunodeficiency.

• A. Both the Assertion and the Reason are true and the Reason is a correct explanation of the Assertion.
• B. Both the Assertion and Reason are true but the Reason is not a correct explanation of the Assertion.
• C. The Assertion is true but the Reason is false.
• D. Both the Assertion and Reason are false.
• E. The Assertion is false but Reason is true.

Answer 1

The correct option is A Both the Assertion and the Reason are true and the Reason is a correct explanation of the Assertion.

Severe Combined Immunodeficiency is a primary immune deficiency characterized by the severe defects in both the T- and B-lymphocyte systems. This usually results in the onset of one or more serious infections within the first few months of life. These infections are usually serious and may even be life-threatening, they may include pneumonia, meningitis or bloodstream infections. There are several forms of SCID. The most common type is linked to the X-chromosome, making this form affect only males. Other forms of SCID usually follow an autosomal recessive inheritance pattern or are the result of spontaneous mutations. One of these other forms is linked to a deficiency of the enzyme adenosine deaminase (ADA) while other cases of SCID are caused by a variety of other defects.