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Question

Assertion :The antibodies separated from serum are homogeneous. Reason: Monoclonal antibodies are homogeneous immunological reagents.

A
Both Assertion and Reason are correct and Reason is the correct explanation for Assertion.
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B
Both Assertion and Reason are correct but Reason is not the correct explanation for Assertion.
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C
Assertion is correct but Reason is incorrect.
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D
Assertion is incorrect but Reason is correct.
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Solution

The correct option is D Assertion is incorrect but Reason is correct.
For the research and medical purpose, antibodies are usually obtained from the serum of hyperimmunized animals. Since animals are hyperimmunized, they have the high amount of single type of antibodies. However, other antibodies are also present because cells continue to produce the variety of antibodies as well. Hence, antibodies separated from serum are heterogeneous. This antibody preparation does not have the desired specificity and hence cannot be used for screening or medical purpose. Monoclonal antibodies are homogeneous immunological reagents. These preparations contain only one type of antibody in it. These are used for screening and diagnosis purpose due to its specificity.
Thus, the correct answer is option D.

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