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Harmful Microbes

Autosomal mut...

Question

Autosomal mutant allele Hbs causes

A

Thalassemia

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B

Albinism

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C

Sickle cell anaemia

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D

Agammaglobulinemia

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Solution

The correct option is D Sickle cell anaemia
Sickle aneamia is a disorder where the shape of haemoglobin acquires the shape of a sickle. The autosomal mutant allele for sickle cell anaemia is Hbs. The homozygous recessive gene causing sickle cell anaemia is Hbs.

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Q. Assertion :Sickle-cell anaemia is an autosomal linked recessive disorder that can be transmitted if both parents are heterozygous for the gene. Reason: In sickle-cell anaemia, haemoglobin molecule undergoes polymerisation under low oxygen tension causing the change in shape of RBC.

Q. A man and a women who both appear normal have a child together, who has sickle cell anaemia. Sickle cell anaemia is an autosomal recessive trait. The woman becomes pregnant again and is told that she is carrying fraternal twins. What is the probability that both of the couple's twins will develop sickle cell anaemia

Q. Match the human genetic disorders with the causative abnormal chromosomes.

	List I		List II
A	Sickle cell anaemia	1	Sex linked (X chromosome)
B	Colour blindness	2	Autosomal chromosome 7
C	Phenylketonuria	3	Autosomal chromosome 11
D	Cystic fibrosis	4	Autosomal chromosome 4
E	Huntington's disease	5	Autosomal chromosome 12

Q. Match the column.

a	Sickle cell anaemia	$1$	Sex-linked
b	Colour blindness	$2$	Autosomal	$7$
c	Phenyl ketonuria	$3$	Autosomal chromosome	$11$
d	Cystic fibrosis	$4$	Autosomal chromosome	$4$
e	Huntigton's chorea	$5$	Autosomal chromosome	$12$

Q. Mr. Kapoor has Bb autosomal gene pair and d allele sex-linked. What shall be proportion of Bd in sperms?

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