Question

Besides better aeration and mixing properties, what other advantages do stirred tank bioreactors to have over shake flasks?

Answer 1

Besides better aeration and mixing properties, stirred tank bioreactors to have many features that help maintain optimal conditions of temperature, pH, substrate, salts, vitamins, oxygen, etc, and make them more advantageous than a shake flask. These features are:
(i) agitator system,
(ii) oxygen delivery system
(iii) temperature control system
(iv) PH control system

(v) fermentation is contamination free
(vi) Sampling ports so that small volumes of the culture can be withdrawn periodically.