The correct option is
C Nervous system
Botulism is caused by
Clostridium botulinum. The organism releases a neurotoxin which acts on the nerves. The neurotoxin enters the nerve cells and interferes with the release of acetylcholine so the nerve cannot stimulate the muscle to contract. The toxin paralyzes the nerves so that the muscles cannot contract.
So, the correct answer is 'Nervous system'