Question

Calcium is required for functioning of enzyme

• A. Fumarase
• B. ATP-ase
• C. Succinate thiokinase
• D. Isocitrate dehydrogenase

Answer 1

The correct option is D Isocitrate dehydrogenase

Isocitrate dehydrogenase is the enzyme which is plays an active role in conversion of isocitrate to alpha-ketoglutarate and CO${}_2$ during kreb's cycle. Magnesium and calcium are the elements which acts as a cofactor for the enzyme and competes for the active site of isocitrate dehydrogenase. On addition calcium leads to decrease in the rate of chemical reaction as calcium ions are bigger in size than magnesium.

So, the correct answer is option D.