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Question

Carbon monoxide is a pollutant, because it

A
Reacts with oxygen
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B
Inhibits glycolysis
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C
Reacts with haemoglobin
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D
Makes nervous system inactive
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Solution

The correct option is D Reacts with haemoglobin
Carboxyhemoglobin is a stable complex of carbon monoxide and hemoglobin (Hb) that forms in red blood cells. Large quantities of CO hinder the ability of Hb to deliver oxygen to the body, because carboxyhemoglobin forms more readily than does oxyhemoglobin (HbO2).
Hemoglobin contains four heme groups each capable of reversibly binding to one oxygen molecule. Oxygen binding to any of these sites causes a conformational change in the protein, facilitating binding to each of the other sites. Carbon monoxide binds to hemoglobin at the same sites as oxygen, but approximately 200 times more tightly. Hence, option C is correct.

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