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Question

Choose the correct answer from the alternatives given.
Which of the following is not true concerning human growth hormone (hGH)?

A
It has primarily one target tissue in the body
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B
Hypoglycemia can stimulate the release of hGH from the pituitary
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C
Hyposecretion in childhood results in dwarfism
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D
It stimulates the formation of bone
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Solution

The correct option is A It has primarily one target tissue in the body
GH or STH (Growth or Somatotropin Hormone) stimulates body growth, protein, fat, and carbohydrate metabolism. Hyposecretion leads to dwarfism. Hypersecretion of this hormone during the period of skeletal growth causes gigantism characterized by excessive growth of bones, with the enlargement of internal organs as well. Hypersecretion in adulthood causes acromegaly. Here the bones become abnormally thick due to ossification of periosteum and thickening of soft tissues as well.
So the correct answer is it has primarily one target tissue in the body.

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