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Question

Choose the correct statement regarding E1cB reaction?

A
In the first step, leaving group is abstracted
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B
First the proton is abstracted to form the conjugated base
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C
It is a one step process
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D
The reaction proceeds through the conjugate acid of the starting material
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Solution

The correct option is B First the proton is abstracted to form the conjugated base
E1cB reaction i.e, elimination unimolecular conjugate base reaction proceeds by two step mechanism. First, the proton is abstracted to form the conjugate base. Then, the leaving group leaves the substrate to form an alkene. The reaction proceeds through the conjugate base of the starting material.

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