Question

Choose the incorrect statement regarding DNA structure.

• A. Base stacking destabilise DNA double helical structure.
• B. Each chain in DNA constitute sugar-phosphate backbone
• C. Two chains are coiled in right handed fashion
• D. The pitch of the helix has roughly 10 bp.

Answer 1

The correct option is A Base stacking destabilise DNA double helical structure.

Each chain in DNA constitute sugar-phosphate backbone, Two chains are coiled in right-handed fashion in case of B-DNA and the pitch of the helix has roughly 10 bp in it. However, apart from it the base stacking interactions between the nitrogenous bases of the DNA help to stabilize the double helix structure.

So, the correct option is 'Base stacking destabilize DNA double helical structure'.