Choose the options associated with Leber hereditary optic neuropathy.

Arises due to defect in the nuclear DNA

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Arises due to defect in mitochondrial DNA

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(a) and (c) above.

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Is inherited from both father and mother

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Solution

The correct option is B Arises due to defect in mitochondrial DNA
Leber hereditary optic neuropathy is a mitochondrial disorder which leads to vision loss. This happens due to mutation in the mitochondrial DNA. Since mitochondria are contributed by the ovum alone, mitochondrial disorders are inherited from the mother only.

Suggest Corrections

A	B	C
Leber hereditary optic neuropathy	44+XXY	Pale skin,white hairs
Diabetes	45+X	Men are sterile
Albinism	Mitochondrial disorder	Women are sterile
Turner syndrome	Polygenic disorder	This disorder arises during development of zygote.
Klinefelter syndrome	Monogenic disorder	Effect on blood-glucose level